Syphacia muris infection in rats attenuates colorectal carcinogenesis through oxidative stress and gene expression alterations. Implications for modulatory effects by Bryostatin-1
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Effect of bryostatin-1 as an anthelmintic drug on adult Syphacia muris infection in rats
Background: The fact that many laboratory rodent colonies were found to be parasite contaminated suggests a need for eradication to improve their quality for research and testing. However, the most anthelmintic are poisonous, and their application always entails some hazards to the host and interferes with the interpretation of the final results. The use of bryostatin as a potential anthelminti...
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Objective Reproductive toxicity is a major challenge associated with aluminum (Al) exposure. No studies have evaluated the possible effects of curcumin (CUR) on Al-induced reproductive dysfunction. Therefore, this study investigated the effects of CUR treatment on Al-induced reproductive damage. MaterialsAndMethods In this experimental study, 40 male Wistar rats were allocated to five groups (N...
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Oxidative stress is involved in both the pathogenesis and complications of diabetes. ACE inhibitors can slow the progression of cardiac and renal impairments related to diabetes. The effect of enalapril treatment on oxidative stress and tissue injury was studied in hearts, kidneys, and livers from streptozotocin-induced diabetic rats. Twenty-four rats were divided into the following groups: str...
متن کاملOxidative stress, biochemical alterations, and hyperlipidemia in female rats induced by lead chronic toxicity during puberty and post puberty periods
Objective(s):Lead (Pb) is a toxic metal inducing many destructive effects leading to a broad range of physiological, biochemical, and neurological dysfunctions in humans and laboratory animals. Materials and Methods: Here, we investigated the effect of chronic exposure to Pb (50 mg/l) on oxidative stress, hepatotoxicity, nephrotoxicity, and lipid profile of two different age groups of female r...
متن کاملAnthelmintic Efficacy of Ocimum sanctum Against Syphacia muris in Mice
The objective of this study was to investigate the anthelmintic efficacy of herbal drug (Ocimum sanctum) in Syphacia muris infected mice. The drugs were administrated to the infected mice on 18 , th 19 and 20 post infection days. The % efficacy due to test drug was observed on larva and adult worm th th recovery response. Larval and Adult worm recovery were found to be directly proportional to ...
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ژورنال
عنوان ژورنال: Acta Parasitologica
سال: 2018
ISSN: 1896-1851,1230-2821
DOI: 10.1515/ap-2018-0023